Laboratory Reference Intervals in Africa
نویسندگان
چکیده
منابع مشابه
CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
BACKGROUND Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African participants. Using laboratory reference intervals derived from other populations excludes potential trial volunteers in Africa and makes AE assessment challenging. The object...
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BACKGROUND Chemistry safety assessments are interpreted by using chemistry reference ranges (CRRs). Verification of CRRs is time consuming and often requires a statistical background. OBJECTIVES We report on an easy and cost-saving method to verify CRRs. METHODS Using a former method introduced by Sigma Diagnostics, three study sites in sub-Saharan Africa, Bondo, Kenya, and Pretoria and Blo...
متن کاملEvaluation of Locally Established Reference Intervals for Hematology and Biochemistry Parameters in Western Kenya
BACKGROUND Important differences have been demonstrated in laboratory parameters from healthy persons in different geographical regions and populations, mostly driven by a combination of genetic, demographic, nutritional, and environmental factors. Despite this, European and North American derived laboratory reference intervals are used in African countries for patient management, clinical tria...
متن کاملHaematological and biochemical reference intervals for infants and children in Gabon.
OBJECTIVES To establish reference intervals for major haematological and biochemical parameters in Gabonese infants and children. METHODS The reference sample population consisted of 226 healthy infants (4-9 weeks of age) and 185 healthy children (18-60 months of age). Basic red cell parameters as well as total and differential white blood cell counts were performed. Clinical chemistry parame...
متن کاملImmunohaematological reference values for HIV-negative healthy adults in Botswana
BACKGROUND Clinical laboratories in Botswana have relied entirely on the reference intervals for normal immunohaematological values provided by manufacturers' kits and textbooks. OBJECTIVES The aim of this study was to determine the means, medians, 2.5th and 97.5th percentile reference intervals, for normal immunohaematological values in healthy adults in Botswana. METHOD A total of 261 hea...
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تاریخ انتشار 2018